CBF, BOLD, CBV, and CMRO2 fMRI signal temporal dynamics at 500-msec resolution

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CBF, BOLD, CBV, and CMRO(2) fMRI signal temporal dynamics at 500-msec resolution.

PURPOSE To investigate the temporal dynamics of blood oxygenation level-dependent (BOLD), cerebral blood flow (CBF), cerebral blood volume (CBV), and cerebral metabolic rate of oxygen (CMRO(2)) changes due to forepaw stimulation with 500-msec resolution in a single setting. MATERIALS AND METHODS Forepaw stimulation and hypercapnic challenge on rats were studied. CBF and BOLD functional MRI (f...

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CBF, BOLD, CBV and CMRO<sub>2</sub> FMRI at 500-Ms Temporal Resolution

Q. Shen, H. Ren, T. Q. Duong Yerkes Primate Research Center, Emory Unviersity, Atlanta, GA, United States Introduction The intricate neural-vascular coupling associated with changes in neural activity forms the basis for many modern neuroimaging modalities. However, the temporal dynamics of the stimulus-evoked CBF and CBV responses and the resulting BOLD signals remain poorly understood and som...

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Sustained Negative BOLD, CBF, CBV, and CMRO2 fMRI responses to the noxious stimuli in the rat striatum at 11.7T

INTRODUCTION The striatum receives numerous afferent inputs from other brain structures and involves in various aspects of pain processing [1]. We recently reported that noxious forepaw electrical stimulation increases neuronal spike activity but, surprisingly, decreases CBV fMRI in the striatum [2]. The goal of the present study was to investigate this apparent discrepancy by using BOLD, CBF, ...

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Baseline CBF, and BOLD, CBF, and CMRO2 fMRI of visual and vibrotactile stimulations in baboons.

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The magnitude of the blood oxygenation level-dependent (BOLD) signal depends on cerebral blood flow (CBF), cerebral blood volume (CBV) and cerebral metabolic rate of oxygen (CMRO2). Thus, it is difficult to separate CMRO2 changes from CBF and CBV changes. To detect the BOLD signal changes induced only by CMRO2 responses without significant evoked CBF and CBV changes, BOLD and CBV functional mag...

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ژورنال

عنوان ژورنال: Journal of Magnetic Resonance Imaging

سال: 2008

ISSN: 1053-1807,1522-2586

DOI: 10.1002/jmri.21203